Thyroid hormone increases fatty acid use in fetal ovine cardiac myocytes

Abstract Cardiac metabolic substrate preference shifts at parturition from carbohydrates to fatty acids. We hypothesized that thyroid hormone (T3) and palmitic acid (PA) stimulate fetal cardiomyocyte oxidative metabolism capacity. T3 was infused into fetal sheep to a target of 1.5 nM. Dispersed card...

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Bibliographic Details
Main Authors: Natasha Chattergoon, Samantha Louey, Sonnet S. Jonker, Kent L. Thornburg
Format: Article
Language:English
Published: Wiley 2023-11-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.15865