HIV-1 and Amyloid Beta Remodel Proteome of Brain Endothelial Extracellular Vesicles

Amyloid beta (Aβ) depositions are more abundant in HIV-infected brains. The blood–brain barrier, with its backbone created by endothelial cells, is assumed to be a core player in Aβ homeostasis and may contribute to Aβ accumulation in the brain. Exposure to HIV increases shedding of extracellular ve...

Full description

Bibliographic Details
Main Authors: Ibolya E. András, Brice B. Sewell, Michal Toborek
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/8/2741