Emerging epigenetic dynamics in gut-microglia brain axis: experimental and clinical implications for accelerated brain aging in schizophrenia

Emerging epigenetic dynamics in gut-microglia brain axis: experimental and clinical implications for accelerated brain aging in schizophrenia

Brain aging, which involves a progressive loss of neuronal functions, has been reported to be premature in probands affected by schizophrenia (SCZ). Evidence shows that SCZ and accelerated aging are linked to changes in epigenetic clocks. Recent cross-sectional magnetic resonance imaging analyses ha...

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Bibliographic Details
Main Authors: Benneth Ben-Azu, Elisabetta C. del Re, Jared VanderZwaag, Micaël Carrier, Matcheri Keshavan, Mohammadparsa Khakpour, Marie-Ève Tremblay
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
microglia
microbiome
epigenetics
schizophrenia
aging
psychobiotics
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2023.1139357/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2023.1139357/full

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