Neuron-Specific IMP2 Overexpression by Synapsin Promoter-Driven AAV9: A Tool to Study Its Role in Axon Regeneration

Neuron-Specific IMP2 Overexpression by Synapsin Promoter-Driven AAV9: A Tool to Study Its Role in Axon Regeneration

Insulin-like growth factor II mRNA-binding protein (IMP) 2 is one of the three homologues (IMP1-3) that belong to a conserved family of mRNA-binding proteins. Its alternative splice product is aberrantly expressed in human hepatocellular carcinoma, and it is therefore identified as HCC. Previous wor...

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Bibliographic Details
Main Authors: Sarah Blizard, Danielle Park, Natalie O’Toole, Sheeva Norooz, Martin Dela Torre, Young Son, Adam Holstein, Scarlett Austin, Joshua Harman, Samantha Haraszti, Daved Fared, Mei Xu
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cells
Subjects:
adeno-associated viral vector
synapsin promoter
axon regeneration
Insulin-like growth factor II mRNA-binding protein 2
β-actin mRNA localization
Online Access:https://www.mdpi.com/2073-4409/10/10/2654

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https://www.mdpi.com/2073-4409/10/10/2654

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