Immunomodulatory properties of Brucella melitensis lipopolysaccharide determinants on mouse dendritic cells in vitro and in vivo

The lipopolysaccharide (LPS) is a major virulence factor of Brucella, a facultative intracellular pathogenic Gram-negative bacterium. Brucella LPS exhibits a low toxicity and its atypical structure was postulated to delay the host immune response, favouring the establishment of chronic disease. Here...

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Bibliographic Details
Main Authors: Yun Zhao, Sean Hanniffy, Vilma Arce-Gorvel, Raquel Conde-Alvarez, SangKon Oh, Ignacio Moriyón, Sylvie Mémet, Jean-Pierre Gorvel
Format: Article
Language:English
Published: Taylor & Francis Group 2018-12-01
Series:Virulence
Subjects:
Online Access:http://dx.doi.org/10.1080/21505594.2017.1386831