The roles of IRF8 in nonspecific orbital inflammation: an integrated analysis by bioinformatics and machine learning

The roles of IRF8 in nonspecific orbital inflammation: an integrated analysis by bioinformatics and machine learning

Abstract Background Nonspecific Orbital Inflammation (NSOI) represents a persistent and idiopathic proliferative inflammatory disorder, characterized by polymorphous lymphoid infiltration within the orbit. The transcription factor Interferon Regulatory Factor 8 (IRF8), integral to the IRF protein fa...

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Bibliographic Details
Main Authors: Zixuan Wu, Jinfeng Xu, Yi Hu, Xin Peng, Zheyuan Zhang, Xiaolei Yao, Qinghua Peng
Format: Article
Language:English
Published: SpringerOpen 2024-06-01
Series:Journal of Ophthalmic Inflammation and Infection
Subjects:
Nonspecific orbital inflammation (NSOI)
IRF8
Lasso regression
SVM-RFE
Autoimmune inflammatory disorder
Online Access:https://doi.org/10.1186/s12348-024-00410-4

Internet

https://doi.org/10.1186/s12348-024-00410-4

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