Recognition and killing of Brugia malayi microfilariae by human immune cells is dependent on the parasite sample and is not altered by ivermectin treatment

Mass administration of macrocyclic lactones targets the transmission of the causative agents of lymphatic filariasis to their insect vectors by rapidly clearing microfilariae (Mf) from the circulation. It has been proposed that the anti-filarial action of these drugs may be mediated through the host...

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Bibliographic Details
Main Authors: Barbara J. Reaves, Connor Wallis, Ciaran J. McCoy, W. Walter Lorenz, Balazs Rada, Adrian J. Wolstenholme
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
Online Access:http://www.sciencedirect.com/science/article/pii/S221132071830099X