Generation of a transgene-free induced pluripotent stem cell line (SMBCi011-A) from a patient with Prader–Willi syndrome

Prader–Willi syndrome (PWS) is a neurodevelopmental disorder caused by deficiency of paternal gene expression in the 15q11.2-q13 chromosome imprinted region. Hyperphagia and dysgnosia are typical clinical features in the early-childhood of patient. We generated an induced pluripotent stem cell (iPSC...

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Bibliographic Details
Main Authors: Guanghan Jia, Yazhou Cui, Liang Shi, Jing Luan, Jing Wang, Jingxiang Han
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506122000447