Pancreatic stromal Gremlin 1 expression during pancreatic tumorigenesis

Pancreatic stromal Gremlin 1 expression during pancreatic tumorigenesis

Chronic pancreatitis (CP) is a major risk factor of pancreatic ductal adenocarcinoma (PDAC). How CP promotes pancreatic oncogenesis remains unclear. A characteristic feature of PDAC is its prominent desmoplasia in the tumor microenvironment, composed of activated fibroblasts and macrophages. Macroph...

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Bibliographic Details
Main Authors: Joy M. Davis, Binglu Cheng, Madeline M. Drake, Qiang Yu, Baibing Yang, Jing Li, Chunhui Liu, Mamoun Younes, Xiurong Zhao, Jennifer M. Bailey, Qiang Shen, Tien C. Ko, Yanna Cao
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-01-01
Series:Genes and Diseases
Subjects:
Fibroblasts
Gremlin 1
Macrophage migration inhibitory factor
Macrophages
Pancreatic ductal adenocarcinoma
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304220300660

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http://www.sciencedirect.com/science/article/pii/S2352304220300660

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