Targeted proteomics links virulence factor expression with clinical severity in staphylococcal pneumonia

Targeted proteomics links virulence factor expression with clinical severity in staphylococcal pneumonia

IntroductionThe bacterial pathogen Staphylococcus aureus harbors numerous virulence factors that impact infection severity. Beyond virulence gene presence or absence, the expression level of virulence proteins is known to vary across S. aureus lineages and isolates. However, the impact of expression...

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Main Authors: Mariane Pivard, Sylvère Bastien, Iulia Macavei, Nicolas Mouton, Jean-Philippe Rasigade, Florence Couzon, Benjamin Youenou, Anne Tristan, Romain Carrière, Karen Moreau, Jérôme Lemoine, François Vandenesch
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Staphylococcus aureus
community-acquired pneumonia (CAP)
panton valentine leucocidin
tandem mass spectrometer
multiple reaction monitoring (MRM)
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1162617/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2023.1162617/full

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