A single molecule investigation of i-motif stability, folding intermediates, and potential as in-situ pH sensor

A single molecule investigation of i-motif stability, folding intermediates, and potential as in-situ pH sensor

We present a collection of single molecule work on the i-motif structure formed by the human telomeric sequence. Even though it was largely ignored in earlier years of its discovery due to its modest stability and requirement for low pH levels (pH < 6.5), the i-motif has been attracting more...

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Bibliographic Details
Main Authors: Golam Mustafa, Prabesh Gyawali, Jacob A. Taylor, Parastoo Maleki, Marlon V. Nunez, Michael C. Guntrum, Sajad Shiekh, Hamza Balci
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Molecular Biosciences
Subjects:
i-motif
FRET
förster resonance energy transfer
single molecule
PH sensor
folding intermediates
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.977113/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2022.977113/full

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