Quantitative proteomics reveals Polygonum perfoliatum L. ameliorates hepatic steatosis by promoting PPARs/CPT1A/CPT2-mediated fatty acid β-oxidation

Quantitative proteomics reveals Polygonum perfoliatum L. ameliorates hepatic steatosis by promoting PPARs/CPT1A/CPT2-mediated fatty acid β-oxidation

Non-alcoholic fatty liver disease (NAFLD) is a predominant contributor to end-stage liver disease in the forthcoming decades. Polygonum perfoliatum L. (PPL) is an herbal medicine with anti-lipid peroxidation and anti-inflammatory properties. However, detailed hepatoprotective effects of PPL against...

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Bibliographic Details
Main Authors: Guanjie Liu, Ling Chang, Yihan Qian, Jiacheng Lin, Zhi Shang, Min Xu, Fang Wang, Xuehua Sun, Yun Jiang, Yueqiu Gao, Xiaoni Kong
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Pharmacology
Subjects:
quantitative proteomics
hepatic steatosis
polygonum perfoliatum L.
fatty acid β oxidation
lipid metabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1016129/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1016129/full

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