VPS35 promotes cell proliferation via EGFR recycling and enhances EGFR inhibitors response in gastric cancerResearch in context

VPS35 promotes cell proliferation via EGFR recycling and enhances EGFR inhibitors response in gastric cancerResearch in context

Summary: Background: Vacuolar protein sorting-associated protein 35 (VPS35) is a core component of the retromer complex which mediates intracellular protein transport. It is well known that dysfunctional VPS35 functions in the accumulation of pathogenic proteins. In our previous study, VPS35 was fo...

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Bibliographic Details
Main Authors: Junxian Yu, Haoran Feng, Qingqing Sang, Fangyuan Li, Mengdi Chen, Beiqin Yu, Zhuoqing Xu, Tao Pan, Xiongyan Wu, Junyi Hou, Zhenggang Zhu, Chao Yan, Liping Su, Jianfang Li, Bingya Liu
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:EBioMedicine
Subjects:
VPS35
Retromer
EGFR
Erlotinib
Gastric cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396423000166

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http://www.sciencedirect.com/science/article/pii/S2352396423000166

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