Microwave-Assisted, One-Pot Synthesis of Doxycycline under Heterogeneous Catalysis in Water

The selective synthesis of active pharmaceutical molecules is a challenging issue, particularly when attempting to make the reactions even more sustainable. The present work focuses on the microwave-assisted hydrogenolysis of oxytetracycline to selectively produce α-doxycycline. Although the combina...

Full description

Bibliographic Details
Main Authors: Fabio Bucciol, Elia Maffeis, Emanuela Calcio Gaudino, László Jicsinszky, Silvia Tagliapietra, Alessandro Barge, Cristina Prandi, Giancarlo Cravotto
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Antibiotics
Subjects:
Online Access:https://www.mdpi.com/2079-6382/10/9/1084