Nicotinamide enhances osteoblast differentiation through activation of the mitochondrial antioxidant defense system

Abstract Although the normal physiological level of oxidative stress is beneficial for maintaining bone homeostasis, imbalance between reactive oxygen species (ROS) production and antioxidant defense can cause various bone diseases. The purpose of this study was to determine whether nicotinamide (NA...

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Bibliographic Details
Main Authors: Heein Yoon, Seung Gwa Park, Hyun-Jung Kim, Hye-Rim Shin, Ki-Tae Kim, Young-Dan Cho, Jae-I Moon, Min-Sang Park, Woo-Jin Kim, Hyun-Mo Ryoo
Format: Article
Language:English
Published: Nature Publishing Group 2023-07-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-023-01041-w