Development and Evaluation of Raloxifene-Hydrochloride-Loaded Supersaturatable SMEDDS Containing an Acidifier

Raloxifene hydrochloride (RLH) was formulated into a pH-modified supersaturatable self-microemulsifying drug delivery system (S-SMEDDS) to increase drug solubility and dissolution rate. Optimal formulations of pH-modified S-SMEDDSs were developed by incorporating hydroxypropyl-cellulose-L as a preci...

Full description

Bibliographic Details
Main Authors: Jong-Hwa Lee, Hak Hyung Kim, Young Ho Cho, Tae-Sung Koo, Gye Won Lee
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Pharmaceutics
Subjects:
Online Access:http://www.mdpi.com/1999-4923/10/3/78