PCR-SSCP Analysis and DNA Sequencing as an Important Method for Detecting Mutation of INGI gene in Head and Neck Squamous Cell Carcinomas
Tumor specific mutation of the candidate tumor suppressor gene INGI ws demonstrated using PCR-SSCP and DNA sequencing analysis. The mutant sample showed an amino acid change from aspangine (AAC) to serine (AGC) at codon 214 in the INGI gene from the DNA of head and neck cancer cells. The result prov...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Faculty of Dentistry, Universitas Indonesia
2015-11-01
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| Series: | Journal of Dentistry Indonesia |
| Online Access: | http://jdentistry.ui.ac.id/index.php/JDI/article/view/923 |