The relationship between synovial inflammation, structural pathology, and pain in post-traumatic osteoarthritis: differential effect of stem cell and hyaluronan treatment

Abstract Background Synovitis is implicated in the severity and progression of pain and structural pathology of osteoarthritis (OA). Increases in inflammatory or immune cell subpopulations including macrophages and lymphocytes have been reported in OA synovium, but how the particular subpopulations...

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Bibliographic Details
Main Authors: Cindy C. Shu, Sanaa Zaki, Varshini Ravi, Antonella Schiavinato, Margaret M. Smith, Christopher B. Little
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Arthritis Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13075-020-2117-2