Characterization of gastric cancer-stimulated signaling pathways and function of CTGF in cancer-associated fibroblasts

Characterization of gastric cancer-stimulated signaling pathways and function of CTGF in cancer-associated fibroblasts

Abstract Background Cancer-associated fibroblasts (CAFs) are key components of the tumor microenvironment (TME) that play an important role in cancer progression. Although the mechanism by which CAFs promote tumorigenesis has been well investigated, the underlying mechanism of CAFs activation by nei...

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Bibliographic Details
Main Authors: Kyoung-Min Choi, Boram Kim, Su-Min Lee, Jisoo Han, Ha-Song Bae, Su-Bhin Han, Dagyeong Lee, In-Hye Ham, Hoon Hur, Eunjung Kim, Jae-Young Kim
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Cell Communication and Signaling
Subjects:
Cancer-associated fibroblasts (CAFs)
Tumor microenvironment (TME)
Gastric cancer (GC)
Connective tissue growth factor (CTGF)
Online Access:https://doi.org/10.1186/s12964-023-01396-7

Internet

https://doi.org/10.1186/s12964-023-01396-7

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