Endothelial and smooth muscle cells from abdominal aortic aneurysm have increased oxidative stress and telomere attrition.

BACKGROUND: Abdominal aortic aneurysm (AAA) is a complex multi-factorial disease with life-threatening complications. AAA is typically asymptomatic and its rupture is associated with high mortality rate. Both environmental and genetic risk factors are involved in AAA pathogenesis. Aim of this study...

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Main Authors: Giuseppe Cafueri, Federica Parodi, Angela Pistorio, Maria Bertolotto, Francesco Ventura, Claudio Gambini, Paolo Bianco, Franco Dallegri, Vito Pistoia, Annalisa Pezzolo, Domenico Palombo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3325957?pdf=render