Human Papillomaviruses Preferentially Recruit DNA Repair Factors to Viral Genomes for Rapid Repair and Amplification

Human Papillomaviruses Preferentially Recruit DNA Repair Factors to Viral Genomes for Rapid Repair and Amplification

ABSTRACT High-risk human papillomaviruses (HPVs) activate the ataxia telangiectasia mutated-dependent (ATM) DNA damage response as well as the ataxia telangiectasia mutated-dependent DNA-related (ATR) pathway in the absence of external DNA damaging agents for differentiation-dependent genome amplifi...

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Bibliographic Details
Main Authors: Kavi Mehta, Laimonis Laimins
Format: Article
Language:English
Published: American Society for Microbiology 2018-03-01
Series:mBio
Subjects:
ATM
ATR
BRCA1
DNA damage response
double-strand breaks
H2AX
Online Access:https://journals.asm.org/doi/10.1128/mBio.00064-18

Internet

https://journals.asm.org/doi/10.1128/mBio.00064-18

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