Reprogramming of tumor-associated macrophages via NEDD4-mediated CSF1R degradation by targeting USP18

Reprogramming of tumor-associated macrophages via NEDD4-mediated CSF1R degradation by targeting USP18

Summary: Tumor-associated myeloid cells modulate the tumor microenvironment and affect tumor progression. Type I interferon (IFN-I) has multiple effects on tumors and immune response, and ubiquitin-specific peptidase 18 (USP18) functions as a negative regulator of IFN-I signal transduction. This stu...

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Bibliographic Details
Main Authors: Sayuri Miyauchi, Kei-ichiro Arimoto, Mengdan Liu, Yue Zhang, Dong-Er Zhang
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Cell Reports
Subjects:
CP: Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723015723

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http://www.sciencedirect.com/science/article/pii/S2211124723015723

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