Cellular Senescence as the Pathogenic Hub of Diabetes-Related Wound Chronicity

Cellular Senescence as the Pathogenic Hub of Diabetes-Related Wound Chronicity

Diabetes is constantly increasing at a rate that outpaces genetic variation and approaches to pandemic magnitude. Skin cells physiology and the cutaneous healing response are progressively undermined in diabetes which predisposes to lower limb ulceration, recidivism, and subsequent lower extremities...

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Bibliographic Details
Main Authors: Jorge A. Berlanga-Acosta, Gerardo E. Guillén-Nieto, Nadia Rodríguez-Rodríguez, Yssel Mendoza-Mari, Maria Luisa Bringas-Vega, Jorge O. Berlanga-Saez, Diana García del Barco Herrera, Indira Martinez-Jimenez, Sandra Hernandez-Gutierrez, Pedro A. Valdés-Sosa
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Endocrinology
Subjects:
senescence
proliferative senescence
chronic wounds
diabetic ulcers
aging
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.573032/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2020.573032/full

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