Combined Cytotoxic Effect of Inhibitors of Proteostasis on Human Colon Cancer Cells

Combined Cytotoxic Effect of Inhibitors of Proteostasis on Human Colon Cancer Cells

Despite significant progress in the diagnosis and treatment of colorectal cancer, drug resistance continues to be a major limitation of therapy. In this regard, studies aimed at creating combination therapy are gaining popularity. One of the most promising adjuvants are inhibitors of the proteostasi...

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Bibliographic Details
Main Authors: Alina D. Nikotina, Snezhana A. Vladimirova, Nadezhda E. Kokoreva, Elena Y. Komarova, Nikolay D. Aksenov, Sergey Efremov, Elizaveta Leonova, Rostislav Pavlov, Viktor G. Kartsev, Zhichao Zhang, Boris A. Margulis, Irina V. Guzhova
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Pharmaceuticals
Subjects:
colorectal cancer
primary tumor cells
combinatorial therapy
HSF1
Hsp70
chloroquine
Online Access:https://www.mdpi.com/1424-8247/15/8/923

Internet

https://www.mdpi.com/1424-8247/15/8/923

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