Crizotinib-Induced Abnormal Signal Processing in the Retina.

Molecular target therapy for cancer is characterized by unique adverse effects that are not usually observed with cytotoxic chemotherapy. For example, the anaplastic lymphoma kinase (ALK)-tyrosine kinase inhibitor crizotinib causes characteristic visual disturbances, whereas such effects are rare wh...

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Bibliographic Details
Main Authors: Toshiyuki Ishii, Shunichiro Iwasawa, Ryota Kurimoto, Akemi Maeda, Yuichi Takiguchi, Makoto Kaneda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4535857?pdf=render