Importance and Uncertainty of <i>λ</i>-Estimation for Box–Cox Transformations to Compute and Verify Reference Intervals in Laboratory Medicine

Reference intervals play an important role in medicine, for instance, for the interpretation of blood test results. They are defined as the central 95% values of a healthy population and are often stratified by sex and age. In recent years, so-called indirect methods for the computation and validati...

Full description

Bibliographic Details
Main Authors: Frank Klawonn, Neele Riekeberg, Georg Hoffmann
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Stats
Subjects:
Online Access:https://www.mdpi.com/2571-905X/7/1/11