VDAC1: From structure to cancer therapy

Here, we review current evidence pointing to the function of VDAC1 in cell life and death, and highlight these functions in relation to cancer. Found at the outer mitochondrial membrane, VDAC1 assumes a crucial position in the cell, controlling the metabolic cross-talk between mitochondria and the r...

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Bibliographic Details
Main Authors: Varda eShoshan-Barmatz, Dario eMizrachi
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-11-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00164/full