Pangenome Analytics Reveal Two-Component Systems as Conserved Targets in ESKAPEE Pathogens

Pangenome Analytics Reveal Two-Component Systems as Conserved Targets in ESKAPEE Pathogens

ABSTRACT The two-component system (TCS) helps bacteria sense and respond to environmental stimuli through histidine kinases and response regulators. TCSs are the largest family of multistep signal transduction processes, and they are involved in many important cellular processes such as antibiotic r...

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Bibliographic Details
Main Authors: Akanksha Rajput, Yara Seif, Kumari Sonal Choudhary, Christopher Dalldorf, Saugat Poudel, Jonathan M. Monk, Bernhard O. Palsson
Format: Article
Language:English
Published: American Society for Microbiology 2021-02-01
Series:mSystems
Subjects:
ESKAPEE pathogens
pangenomic analysis
two-component systems
antibiotic resistance
genomic architecture
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00981-20

Internet

https://journals.asm.org/doi/10.1128/mSystems.00981-20

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