Connexin 43 and Connexin 26 Involvement in the Ponatinib-Induced Cardiomyopathy: Sex-Related Differences in a Murine Model

Connexin 43 and Connexin 26 Involvement in the Ponatinib-Induced Cardiomyopathy: Sex-Related Differences in a Murine Model

Cardiac connexins (Cxs) are proteins responsible for proper heart function. They form gap junctions that mediate electrical and chemical signalling throughout the cardiac system, and thus enable a synchronized contraction. Connexins can also individually participate in many signal transduction pathw...

Full description

Bibliographic Details
Main Authors: Rosalinda Madonna, Stefania Moscato, Enza Polizzi, Damiana Pieragostino, Maria Concetta Cufaro, Piero Del Boccio, Francesco Bianchi, Raffaele De Caterina, Letizia Mattii
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
connexin
heart
mouse model
ponatinib
Notch1
sex-dependent differences
Online Access:https://www.mdpi.com/1422-0067/22/11/5815

Internet

https://www.mdpi.com/1422-0067/22/11/5815

Similar Items