Locating macromolecular assemblies in cells by 2D template matching with cisTEM

For a more complete understanding of molecular mechanisms, it is important to study macromolecules and their assemblies in the broader context of the cell. This context can be visualized at nanometer resolution in three dimensions (3D) using electron cryo-tomography, which requires tilt series to be...

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Bibliographic Details
Main Authors: Bronwyn A Lucas, Benjamin A Himes, Liang Xue, Timothy Grant, Julia Mahamid, Nikolaus Grigorieff
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/68946