TGF-β1 in plasma and cerebrospinal fluid can be used as a biological indicator of chronic pain in patients with osteoarthritis.

<h4>Introduction</h4>Previous studies have demonstrated that cytokines, transforming growth factor (TGF-β1), and brain-derived neurotrophic factor (BDNF) can impact the intensity of pain in rodents. However, the roles of cytokines, TGF-β1 and BDNF in humans with chronic pain in osteoarth...

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Bibliographic Details
Main Authors: Yen-Chin Liu, Hung-Tsung Hsiao, Jeffrey Chi-Fei Wang, Tzu-Cheng Wen, Shiou-Lan Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0262074