3D additive manufactured composite scaffolds with antibiotic-loaded lamellar fillers for bone infection prevention and tissue regeneration

3D additive manufactured composite scaffolds with antibiotic-loaded lamellar fillers for bone infection prevention and tissue regeneration

Bone infections following open bone fracture or implant surgery remain a challenge in the orthopedics field. In order to avoid high doses of systemic drug administration, optimized local antibiotic release from scaffolds is required. 3D additive manufactured (AM) scaffolds made with biodegradable po...

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Bibliographic Details
Main Authors: María Cámara-Torres, Stacy Duarte, Ravi Sinha, Ainhoa Egizabal, Noelia Álvarez, Maria Bastianini, Michele Sisani, Paolo Scopece, Marco Scatto, Alessandro Bonetto, Antonio Marcomini, Alberto Sanchez, Alessandro Patelli, Carlos Mota, Lorenzo Moroni
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2021-04-01
Series:Bioactive Materials
Subjects:
Melt extrusion additive manufacturing
Antibiotic delivery
Lamellar inorganic fillers
Bone infection
Bone regeneration
Human mesenchymal stromal cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X20302516

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http://www.sciencedirect.com/science/article/pii/S2452199X20302516

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