Transition-metal catalyzed synthesis of Ketoprofen

Transition metal-catalyzed reactions including carbonylations, hydrovinylations and hydrogenations have been applied in the synthesis of alpha-(3-benzoylphenyl)propanoic acid (Ketoprofen). 3-Vinylbenzophenone was obtained from 3-bromobenzophenone by a Pd-catalyzed Heck coupling reaction. Pd-catalyze...

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Bibliographic Details
Main Authors: Ramminger Carolina, Zim Danilo, Lando Vanusa R., Fassina Viviane, Monteiro Adriano L.
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2000-01-01
Series:Journal of the Brazilian Chemical Society
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532000000200002