ESCRT-III drives the final stages of CUPS maturation for unconventional protein secretion

The unconventional secretory pathway exports proteins that bypass the endoplasmic reticulum. In Saccharomyces cerevisiae, conditions that trigger Acb1 secretion via this pathway generate a Grh1 containing compartment composed of vesicles and tubules surrounded by a cup-shaped membrane and collective...

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Bibliographic Details
Main Authors: Amy J Curwin, Nathalie Brouwers, Manuel Alonso Y Adell, David Teis, Gabriele Turacchio, Seetharaman Parashuraman, Paolo Ronchi, Vivek Malhotra
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-04-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/16299