Systems Drug Discovery for Diffuse Large B Cell Lymphoma Based on Pathogenic Molecular Mechanism via Big Data Mining and Deep Learning Method

Systems Drug Discovery for Diffuse Large B Cell Lymphoma Based on Pathogenic Molecular Mechanism via Big Data Mining and Deep Learning Method

Diffuse large B cell lymphoma (DLBCL) is an aggressive heterogeneous disease. The most common subtypes of DLBCL include germinal center b-cell (GCB) type and activated b-cell (ABC) type. To learn more about the pathogenesis of two DLBCL subtypes (i.e., DLBCL ABC and DLBCL GCB), we firstly construct...

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Bibliographic Details
Main Authors: Shan-Ju Yeh, Tsun-Yung Yeh, Bor-Sen Chen
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
diffuse large B cell lymphoma (DLBCL)
deep neural network
drug discovery
drug combination
Online Access:https://www.mdpi.com/1422-0067/23/12/6732

Internet

https://www.mdpi.com/1422-0067/23/12/6732

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