Serum O-glycosylated hepatitis B surface antigen levels in patients with chronic hepatitis B during nucleos(t)ide analog therapy

Abstract Background Serum hepatitis B surface antigen (HBsAg) is a component of both hepatitis B virus (HBV) virions and non-infectious subviral particles (SVPs). Recently, O-glycosylation of the PreS2 domain of middle HBsAg protein has been identified as a distinct characteristic of genotype C HBV...

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Bibliographic Details
Main Authors: Ayato Murata, Kiyohiko Angata, Maki Sogabe, Shunsuke Sato, Takafumi Ichida, Hisashi Narimatsu, Takuya Genda
Format: Article
Language:English
Published: BMC 2022-05-01
Series:BMC Gastroenterology
Subjects:
Online Access:https://doi.org/10.1186/s12876-022-02352-4