Injectable decellularized cartilage matrix hydrogel encapsulating urine-derived stem cells for immunomodulatory and cartilage defect regeneration

Abstract Reconstruction of complex cartilage defects has remained a great challenge for tissue engineering due to the lack of stem cells and chronic inflammation within the joint. In this study, we have developed an injectable pig cartilage-derived decellularized extracellular matrix (dECM) hydrogel...

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Bibliographic Details
Main Authors: Junfeng Zeng, Liping Huang, Huazhang Xiong, Qianjin Li, Chenyu Wu, Yizhou Huang, Huiqi Xie, Bin Shen
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-022-00269-w