The Immunomodulatory Effects of Dexamethasone on Neoadjuvant Chemotherapy for Triple-Negative Breast Cancer

The Immunomodulatory Effects of Dexamethasone on Neoadjuvant Chemotherapy for Triple-Negative Breast Cancer

Abstract Introduction The immunomodulatory impact of corticosteroids and concurrent chemotherapy is poorly understood within triple-negative breast cancer (TNBC). On a biochemical level, steroids have been linked to the signaling of chemotherapy-resistant pathways. However, on a clinical level, ster...

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Main Authors: Kai Conrad Cecil Johnson, Daniel Goldstein, Jasmin Tharakan, Dionisia Quiroga, Mahmoud Kassem, Michael Grimm, Abdul Miah, Craig Vargo, Michael Berger, Preeti Sudheendra, Ashley Pariser, Margaret E. Gatti-Mays, Nicole Williams, Daniel Stover, Sagar Sardesai, Robert Wesolowski, Bhuvaneswari Ramaswamy, Gary Tozbikian, Patrick M. Schnell, Mathew A. Cherian
Format: Article
Language:English
Published: Adis, Springer Healthcare 2023-06-01
Series:Oncology and Therapy
Subjects:
Triple-negative breast cancer (TNBC)
Pathological complete response (pCR)
Steroids
Neoadjuvant chemotherapy
Taxane
Anthracycline
Online Access:https://doi.org/10.1007/s40487-023-00235-6

Internet

https://doi.org/10.1007/s40487-023-00235-6

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