Evaluation of T-cell aging-related immune phenotypes in the context of biological aging and multimorbidity in the Health and Retirement Study

Evaluation of T-cell aging-related immune phenotypes in the context of biological aging and multimorbidity in the Health and Retirement Study

Abstract Background Cellular changes in adaptive immune system accompany the process of aging and contribute to an aging-related immune phenotype (ARIP) characterized by decrease in naïve T-cells (TN) and increase in memory T-cells (TM). A population-representative marker of ARIP and its association...

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Bibliographic Details
Main Authors: Ramya Ramasubramanian, Helen C. S. Meier, Sithara Vivek, Eric Klopack, Eileen M. Crimmins, Jessica Faul, Janko Nikolich-Žugich, Bharat Thyagarajan
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Immunity & Ageing
Subjects:
Immune aging
Adaptive immunity
Biological aging
Multimorbidity
Health and Retirement Study
Online Access:https://doi.org/10.1186/s12979-022-00290-z

Internet

https://doi.org/10.1186/s12979-022-00290-z

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