Biomimetic chitosan scaffolds with long-term controlled release of nerve growth factor repairs 20-mm-long sciatic nerve defects in rats

Biomimetic chitosan scaffolds with long-term controlled release of nerve growth factor repairs 20-mm-long sciatic nerve defects in rats

Although autogenous nerve transplantation is the gold standard for treating peripheral nerve defects of considerable length, it still has some shortcomings, such as insufficient donors and secondary injury. Composite chitosan scaffolds loaded with controlled release of nerve growth factor can promot...

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Bibliographic Details
Main Authors: Fa-Dong Liu, Hong-Mei Duan, Fei Hao, Wen Zhao, Yu-Dan Gao, Peng Hao, Zhao-Yang Yang, Xiao-Guang Li
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Neural Regeneration Research
Subjects:
axon; chitosan; functional recovery; myelin sheath; nerve growth factor; peripheral nerve injury; pseudorabies virus; regeneration; scaffold; sciatic nerve
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2022;volume=17;issue=5;spage=1146;epage=1155;aulast=Liu

Internet

http://www.nrronline.org/article.asp?issn=1673-5374;year=2022;volume=17;issue=5;spage=1146;epage=1155;aulast=Liu

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