Predictive Testing for Tumor Predisposition Syndromes in Pediatric Relatives: An Asian Experience

Predictive Testing for Tumor Predisposition Syndromes in Pediatric Relatives: An Asian Experience

Approximately 10% of pediatric cancer patients possess germline pathogenic/likely pathogenic variants (PV/LPV) in known tumor predisposition genes. Predictive testing is the optimal approach to identify asymptomatic at-risk relatives to guide gene-directed surveillance for early cancer detection and...

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Bibliographic Details
Main Authors: Jianbang Chiang, Jeanette Yuen, Tarryn Shaw, Hui Xuan Goh, Shao-Tzu Li, Eliza Courtney, Joanne Ngeow
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Pediatrics
Subjects:
predictive testing
cascade
hereditary cancer
pediatric
Asia
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2020.568528/full

Internet

https://www.frontiersin.org/articles/10.3389/fped.2020.568528/full

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