Selenoprotein K enhances STING oligomerization to facilitate antiviral response.

Stimulator-of-interferon gene (STING) is a vital element of the innate immune system against DNA viruses. Optimal activation of STING is crucial for maintaining immune homeostasis and eliminating invading viruses, and the oligomerization of STING is an essential prerequisite for STING activation. Ho...

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Bibliographic Details
Main Authors: Lin Lv, Li Chai, Jie Wang, Mengge Wang, Danhui Qin, Hui Song, Yue Fu, Chunyuan Zhao, Jihui Jia, Wei Zhao, Mutian Jia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-04-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1011314