Therapeutic Vaccination Refocuses T-cell Responses Towards Conserved Regions of HIV-1 in Early Treated Individuals (BCN 01 study)

Therapeutic Vaccination Refocuses T-cell Responses Towards Conserved Regions of HIV-1 in Early Treated Individuals (BCN 01 study)

Background: Strong and broad antiviral T-cell responses targeting vulnerable sites of HIV-1 will likely be a critical component for any effective cure strategy. Methods: BCN01 trial was a phase I, open-label, non-randomized, multicenter study in HIV-1-positive individuals diagnosed and treated durin...

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Bibliographic Details
Main Authors: Beatriz Mothe, Christian Manzardo, Alvaro Sanchez-Bernabeu, Pep Coll, Sara Morón-López, Maria C. Puertas, Miriam Rosas-Umbert, Patricia Cobarsi, Roser Escrig, Núria Perez-Alvarez, Irene Ruiz, Cristina Rovira, Michael Meulbroek, Alison Crook, Nicola Borthwick, Edmund G. Wee, Hongbing Yang, Jose M. Miró, Lucy Dorrell, Bonaventura Clotet, Javier Martinez-Picado, Christian Brander, Tomáš Hanke
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:EClinicalMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537019300872

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http://www.sciencedirect.com/science/article/pii/S2589537019300872

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