HiCcompare: an R-package for joint normalization and comparison of HI-C datasets

HiCcompare: an R-package for joint normalization and comparison of HI-C datasets

Abstract Background Changes in spatial chromatin interactions are now emerging as a unifying mechanism orchestrating the regulation of gene expression. Hi-C sequencing technology allows insight into chromatin interactions on a genome-wide scale. However, Hi-C data contains many DNA sequence- and tec...

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Bibliographic Details
Main Authors: John C. Stansfield, Kellen G. Cresswell, Vladimir I. Vladimirov, Mikhail G. Dozmorov
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BMC Bioinformatics
Subjects:
Hi-C
Chromosome conformation capture
Normalization
Comparison
Differential analysis
HiCcompare
Online Access:http://link.springer.com/article/10.1186/s12859-018-2288-x

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http://link.springer.com/article/10.1186/s12859-018-2288-x

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