Systemic FasL and TRAIL neutralisation reduce leishmaniasis induced skin ulceration.

Systemic FasL and TRAIL neutralisation reduce leishmaniasis induced skin ulceration.

Cutaneous leishmaniasis (CL) is caused by Leishmania infection of dermal macrophages and is associated with chronic inflammation of the skin. L. aethiopica infection displays two clinical manifestations, firstly ulcerative disease, correlated to a relatively low parasite load in the skin, and second...

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Main Authors: Geremew Tasew, Susanne Nylén, Thorsten Lieke, Befekadu Lemu, Hailu Meless, Nicolas Ruffin, Dawit Wolday, Abraham Asseffa, Hideo Yagita, Sven Britton, Hannah Akuffo, Francesca Chiodi, Liv Eidsmo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2953481?pdf=render

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http://europepmc.org/articles/PMC2953481?pdf=render

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