pH-Responsive PEGylated Niosomal Nanoparticles as an Active-Targeting Cyclophosphamide Delivery System for Gastric Cancer Therapy

pH-Responsive PEGylated Niosomal Nanoparticles as an Active-Targeting Cyclophosphamide Delivery System for Gastric Cancer Therapy

A PEGylated niosomal formulation of cyclophosphamide (Nio-Cyclo-PEG) was prepared using a central composite design and characterized in terms of drug loading, size distribution, and average size. The stability of formulations was also studied at different conditions. In vitro cytotoxicity of drug de...

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Bibliographic Details
Main Authors: Farnaz Khodabakhsh, Mahsa Bourbour, Mohammad Tavakkoli Yaraki, Saina Bazzazan, Haleh Bakhshandeh, Reza Ahangari Cohan, Yen Nee Tan
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Molecules
Subjects:
gastric cancer
Cyclophosphamide
Niosome
PEGylation
optimization
drug delivery
Online Access:https://www.mdpi.com/1420-3049/27/17/5418

Internet

https://www.mdpi.com/1420-3049/27/17/5418

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