Harpagoside attenuates local bone Erosion and systemic osteoporosis in collagen-induced arthritis in mice

Harpagoside attenuates local bone Erosion and systemic osteoporosis in collagen-induced arthritis in mice

Abstract Background Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that causes local bone erosion and systemic osteoporosis. Harpagoside (HAR), an iridoid glycoside, has various pharmacological effects on pain, arthritis, and inflammation. Our previous study suggests that HAR...

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Bibliographic Details
Main Authors: Ju-Young Kim, Yoon-Hee Cheon, Sung-Jun Ahn, Sung Chul Kwak, Chong Hyuk Chung, Chang Hoon Lee, Myeung Su Lee
Format: Article
Language:English
Published: BMC 2022-08-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Collagen-induced arthritis model
Harpagoside
Inflammation
Osteoclasts
Rheumatoid arthritis
Online Access:https://doi.org/10.1186/s12906-022-03694-y

Internet

https://doi.org/10.1186/s12906-022-03694-y

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