Pretreatment with mangafodipir improves liver graft tolerance to ischemia/reperfusion injury in rat.

Ischemia/reperfusion injury occurring during liver transplantation is mainly due to the generation of reactive oxygen species (ROS) upon revascularization. Thus, delivery of antioxidant enzymes might reduce the deleterious effects of ROS and improve liver graft initial function. Mangafodipir trisodi...

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Bibliographic Details
Main Authors: Ismail Ben Mosbah, Yann Mouchel, Julie Pajaud, Catherine Ribault, Catherine Lucas, Alexis Laurent, Karim Boudjema, Fabrice Morel, Anne Corlu, Philippe Compagnon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3511495?pdf=render