Identification of novel drug targets for liver cirrhosis and its potential side-effects by human plasma proteome

Identification of novel drug targets for liver cirrhosis and its potential side-effects by human plasma proteome

Abstract Liver cirrhosis, a common liver disease, currently lacks specific targeted therapies. This study investigates the potential therapeutic effects of serum circulating proteins on cirrhosis from a genetic perspective, and identified six associated plasma proteins (SERPINA1, PSG5, NCAN, APOE, A...

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Bibliographic Details
Main Authors: Qing-Ao Xiao, Wen-Jiang Zhao, Jing Yu, Lei Qin, Xiao-Lin Zhang, Jin Yu
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Durg targets
Mendelian randomization
Proteome-wide mendelian randomization
Cirrhosis
Online Access:https://doi.org/10.1038/s41598-024-80483-2

Internet

https://doi.org/10.1038/s41598-024-80483-2

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