Inverse Modulation of Aurora Kinase A and Topoisomerase IIα in Normal and Tumor Breast Cells upon Knockdown of Mitochondrial ASncmtRNA

Inverse Modulation of Aurora Kinase A and Topoisomerase IIα in Normal and Tumor Breast Cells upon Knockdown of Mitochondrial ASncmtRNA

Breast cancer is currently the most diagnosed form of cancer and the leading cause of death by cancer among females worldwide. We described the family of long non-coding mitochondrial RNAs (ncmtRNAs), comprised of sense (SncmtRNA) and antisense (ASncmtRNA) members. Knockdown of ASncmtRNAs using anti...

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Bibliographic Details
Main Authors: Maximiliano F. Bendek, Christopher Fitzpatrick, Emanuel Jeldes, Anne Boland, Jean-François Deleuze, Nicole Farfán, Jaime Villegas, Gino Nardocci, Martín Montecino, Luis O. Burzio, Verónica A. Burzio
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Non-Coding RNA
Subjects:
ncRNA
Aurora kinase A
toposiomerase IIα
breast cancer
antisense therapy
Online Access:https://www.mdpi.com/2311-553X/9/5/59

Internet

https://www.mdpi.com/2311-553X/9/5/59

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